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Barbro Hedin Skogman Disputationsdatum: Epidemiology and clinical manifestations of Lyme borreliosis in childhood. Furthermore, the sample size of negative controls could have been larger than 49, but it could unfortunately not be achieve during the time period and in clinical setting of the study. Neuroborreliosis NB is a disseminated form of the disease, in which the spirochetes invade the nervous system. Immunförsvarets signalsubstanser, som analyserades i ryggvätska och blod, visade sig ha en viss profil hos barn med Neuroborrelios jämfört med barn utan Borrelia-infektion, men även jämfört med vuxna med Neuroborrelios.

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Received Jun 25; Accepted Dec

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Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury

Results in this thesis support the notion that mononuclear pleocytosis in CSF, in patients being evaluated for NB, indicates that they are true NB cases despite the fact that an antibody response cannot yet be visualized. Consequently, early antibiotic treatment in NB seems to be the correct course of action and over-treatment is not a substantial problem. The diagnosis of Lyme neuroborreliosis LNB in Europe is based on clinical symptoms and laboratory findings, including pleocytosis in the cerebrospinal fluid CSF and intrathecal anti- Borrelia antibody production, in accordance with the guidelines [ 6 ]. Patients were not included from all seven paediatric clinics so this control sample cannot be considered as representative of children with each diagnosis. Dessutom har jag tittat närmare på vissa signalsubstanser inom immunförsvaret i blod och ryggvätska och vilken roll signalsubstanserna spelar för förlopp och utläkning av infektionen.

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